Hyperglycemia-induced mitochondrial dysfunction here plays a key role in the pathogenesis of diabetic cardiomyopathy.Injured mitochondrial segments are separated by mitochondrial fission and eliminated by autophagic sequestration and subsequent degradation in the lysosome, a process termed mitophagy.However, it remains poorly understood how high gl
This paper introduces campicon.com a new color image superresolution algorithm in an adaptive, robust M-estimation framework.Using a robust error norm in the objective function, and adapting the estimation process to each of the low-resolution frames, the proposed method effectively suppresses the outliers due to violations of the assumed observati
Playability is an attribute that refers to the ability to stimulate individual responses or collective action in an immersive activity in an exploratory way.Playability is an important component of the enjoyment and well-being of urban dwellers, has the potential to stimulate urban vitality and is an important expression of the inclusiveness and eq
IntroductionThe full extent of interactions between human immunodeficiency virus (HIV) infection, injection drug use, and the human microbiome is unclear.In this study, we examined the microbiomes of HIV-positive and HIV-negative individuals, both drug-injecting and non-injecting, to identify bacterial community changes in response to HIV and drug
Adolescence is of particular significance to schizophrenia, since psychosis onset typically occurs in this critical period.Based on the N-methyl-D-aspartate (NMDA) receptor hypofunction hypothesis of schizophrenia, in this study, we investigated whether and how repeated NMDA receptor blockade during adolescence would affect GABAergic interneurons i